Portfolio
“We want to transform scientific founders into business leaders of tomorrow.”
Veronica Breckenridge, First Bight Founder
Between Proof-of-Concept and Early Commercialization
Managing Risks in Biomanufacturing
We have tailored our approach to help companies navigate specific challenges in biomanufacturing.
Science
Exceptional technology and scientific proof point
Our in-house scientific expertise and advisors rigorously vet potential investments to validate the science and its potential. Clear ownership of patents and sound patent strategy.
Commercial
Inflection point and strong early traction
At their key inflection: vetted scientific proof-point and ready for early commercial scale. Product development and/or licensing agreements in place.
Commercial viability and large addressable market
Innovations must have a clear path to commercialization and cost parity. Product revenue of at least $100M per annum.
Execution
Outstanding Founders
Strong founding team combines scientific and operational expertise with high growth potential and drive to grow their business.
Capital
Federal funding access potential
Track record of high-level grants from government bodies and biomanufacturing funding programs.
Outsized exit potential
Minimum 20x potential and valuation of >$1 billion upon exit if successful.
Portfolio Companies
Portfolio Company News
Persephone
Oct 19, 2023
Persephone Biosciences Announces New Collaboration With Kroger Health to Launch AMBROSIA Food as Medicine Study
BioSpace
Oct 17, 2023
Persephone Biosciences and Ginkgo Bioworks Complete Reusable Bacteroides Anaerobic Engineering Toolkit
Cision
July 27, 2023
Building a Better Microbiome
proto.life
April 27, 2023
“Cancer & the Gut Biome” with Stephanie Culler, Ph.D.
Angel Invest Boston
Jan 24, 2023
Kroger Health Establishes Clinical Trial Site Network to Increase Reach and Access to Research Studies
Cision
Sept 20, 2022
Persephone Biosciences Announces First Participant Enrolled in the ARGONAUT Study of Gut Microbiome-Linked Immune Modulation in Cancer Treatment Response
GlobeNewswire
July 19, 2022
Persephone Biosciences, Pioneers In Synthetic Biology, Lands $15M In Seed Funding
Grit Daily
July 19, 2022
Can bacteria in your gut boost cancer therapies? A San Diego startup thinks so
The San Diego-Union Tribune
July 19, 2022
Persephone puts poop to work to explore and heal your gut microbiome
TechCrunch
Visolis
July 30, 2024
Visolis Receives $2.25M DOD Award to Plan for Domestic Facility
U.S. Dept. of Defense
April 10, 2024
Zeon and Visolis collaborating on commercialization of bio-isoprene monomers
Chemical Engineering
October 26, 2023
Goodyear, Visolis partner for bio-based isoprene
Rubber News
July 20, 2023
Harnessing synthetic biology to make sustainable alternatives to petroleum products
MIT
April 24, 2023
Visolis and Ginkgo Bioworks Announce Partnership to Improve Microbial Strain
Ginkgo Bioworks
Jan 11, 2023
Biomanufacturing Startup Visolis Has Raised $8 Million To Make Carbon-Negative Materials
Forbes
Sept 19, 2019
Visolis Recognized as One of “the 50 Next Companies to Disrupt the World”
The Digest
Algenesis
Sept 16, 2024
DoD Releases 12 Awards for Distributed Bioindustrial Manufacturing Program
June 27, 2024
How Biodegradable Polyurethane Could Solve the Microplastic Pollution Problem
March 24, 2024
Algenesis Unveils Groundbreaking Biodegradable TPU Material, Pioneering a Future Without Microplastics
September 21, 2022
Sustainability Matters: Sanuk Debuts Plant-Based, Carbon-Neutral Sneakers + More News
Footwear News
R2dio
Check back soon
Capra Biosciences
July 19, 2024
Capra Biosciences Lands $7.5 Million Project Agreement To Demonstrate Platform To Rapidly Scale Pharmaceutical Ingredient Manufacturing
Capra Biosciences
April 29, 2024
How Microbes Are Changing Manufacturing: Why We Invested in Capra Biosciences
Closed Loop Partners
Industrial Microbes
Nov 19, 2024
Industrial Microbes announces seed round funding
iMicrobes Press
Nov 4, 2024
A low-cost method for bio-based production of acrylic acid
Chemical Engineering
September 14, 2023
DoD Releases Seven Awards for Distributed Bioindustrial Manufacturing Program
BioMADE
September 14, 2023
BioMADE Announces Nine Projects, $18.7 Million to Advance Domestic Bioindustrial Manufacturing and DoD Sustainability Goals
BioMADE
VIA BioFuels
Check back soon
First Bight Ventures
First Bight Ventures is investing in biomanufacturing to solve large-scale challenges to humanity.
First Bight Ventures © 2025