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THE BIOMANUFACTURING CAPITAL PLAYBOOK

Fund The Bio-Revolution Without Burning The Cap Table

Biomanufacturing does not fail because capital is unavailable. It fails when the wrong kind of capital is used at the wrong stage.

The First Bight Biomanufacturing Capital Playbook is a practical guide to funding industrial bio companies with the right mix of equity, grants, debt, tax incentives, project finance, offtake agreements, and strategic capital.

Unlike software companies, industrial biomanufacturing ventures have to fund physical assets - pilot plants, demo facilities, commercial infrastructure, supply chains, and long construction timelines. That means the capital strategy has to be engineered just as carefully as the biology.

Inside the playbook, you’ll learn why successful funding in this sector requires a different approach:

Equity should be a catalyst, not the entire financing plan

Non-dilutive funding should be mapped to technical milestones

Offtake agreements can unlock debt, guarantees, and project finance

Location, policy, and incentives can materially change project economics

Commercial scale requires capital architecture, not just another venture round

The companies that win in industrial bio will be the ones that know how to sequence capital before they need it, protect ownership as they scale, and finance physical infrastructure without relying on equity alone.

Download the Capital Playbook to understand how the next generation of biomanufacturing companies can fund the path from lab to commercial scale.

Our analysis breaks down key insights to scale bio.

Driving sustainable innovation

The Leading Investor in Biomanufacturing

First Bight Ventures is an early stage biomanufacturing investor.

In our first fund, we invested in 7 startups.

Now, we are helping other investors and corporations scale the use of biology throughout manufacturing.

Check Out Our Awesome Portfolio Companies

Beyond Capital

We Partner With Startups To Scale Impact

If you are looking for silent capital, you are in the wrong place.

We Lead Rounds

We write first checks for

seed through series A.

We Take Board Seats

We are actively involved in

strategy and governance.

We Make Introductions

We leverage our relationships to drive meaningful partnerships.

We Drive Efficiencies

We help our portfolio companies proficiently scale operations.

We Mitigate Risks

We identify and reduce scale up risks to increase shareholder value.

We Love Science

We nerd out on technology

and how it drives impact.

TESTIMONIALS

Why Work With Us?

We have created the leading biomanufacturing venture ecosystem.

“First Bight knows how to derisk industrial biotech investments.”

“In a complex, long gestation and capital-intensive space, First Bight stands out for how it actively drives progress; not just funds it.”

- Mario Maia, Ventures @ Novozymes

“Connecting all the dots for startups and corporates."

“Veronica & the First Bight team understand how we fit into the ecosystem, & make valuable introductions to key industry partners.”

- Noah Helman, CEO @ iMicrobes

"First Bight turns lab scale into industrial powerhouses."

“Veronica & the team dive in early, bring Tesla-level technical rigor, and help founders de-risk scale-up so their companies can print cash.”

- Dave McClure, Founder @ 500 Startups

Smiles expected, not guaranteed.

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