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From Flask to factory

Your Guide for Building in Industrial Biotech

Industrial biotech has the potential to reshape how the world manufactures chemicals, materials, and fuels. But the sector is filled with well-funded companies that failed, not because their science was wrong, but because they couldn't survive the brutal economics of commercial scale-up.

First Bight Ventures has studied the wins and the wrecks and distilled what we've learned into The Founder's Guide to Building a Unicorn in Industrial Biotech. Five things you absolutely must do and five mistakes that will put you in the graveyard. The throughline is simple: the companies that make it shift their mindset from solving equations to solving for margins, and they do it earlier than you'd expect.

Software scales at near-zero marginal cost. Your microbe doesn't.

Skip a stage, and you'll pay for it twice.

Technology is not the constraining factor.

Equity-only funding is the silent killer.

Your financial model is only as honest as your DSP assumptions.

Over 80% of industrial biotech failures aren't caused by bad science; they're caused by preventable execution breakdowns.

Ready to make the transition from lab bench to boardroom? Download the guide.

Our learnings to help you build better in bio.

Driving sustainable innovation

The Leading Investor in Biomanufacturing

First Bight Ventures is an early stage biomanufacturing investor.

In our first fund, we invested in 7 startups.

Now, we are helping other investors and corporations scale the use of biology throughout manufacturing.

Beyond Capital

We Partner With Startups To Scale Impact

If you are looking for silent capital, you are in the wrong place.

We Lead Rounds

We write first checks for

seed through series A.

We Take Board Seats

We are actively involved in

strategy and governance.

We Make Introductions

We leverage our relationships to drive meaningful partnerships.

We Drive Efficiencies

We help our portfolio companies proficiently scale operations.

We Mitigate Risks

We identify and reduce scale up risks to increase shareholder value.

We Love Science

We nerd out on technology

and how it drives impact.

TESTIMONIALS

Why Work With Us?

We have created the leading biomanufacturing venture ecosystem.

“First Bight knows how to derisk industrial biotech investments.”

“In a complex, long gestation and capital-intensive space, First Bight stands out for how it actively drives progress; not just funds it.”

- Mario Maia, Ventures @ Novozymes

“Connecting all the dots for startups and corporates."

“Veronica & the First Bight team understand how we fit into the ecosystem, & make valuable introductions to key industry partners.”

- Noah Helman, CEO @ iMicrobes

"First Bight turns lab scale into industrial powerhouses."

“Veronica & the team dive in early, bring Tesla-level technical rigor, and help founders de-risk scale-up so their companies can print cash.”

- Dave McClure, Founder @ 500 Startups

Smiles expected, not guaranteed.

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